The theoretical formula for calculating the internal ballistic correction coefficients is deduced using interior ballistics equations and derivative operation. The correction coefficients of charge weight, propellant web size and projectile mass are calculated for 5.8 mm rifle. The results show that the influences of the factors on the initial velocity and maximum bore pressure of 5.8 mm rifle are the charge weight, propellant web side and projectile mass in order. The charge weight can be controlled accurately, so only the significant effects of propellant’s size and projectile mass on the velocity of 5.8 mm rifle are analyzed by statistical analysis. The analysis result shows that the propellant’s size is more sensitive to velocity compared with projectile mass, which is in accord with the theoretical calculation. It is an effective way to increase the firing accuracy of 5.8 mm rifle by improving the deviation of propellant’s size.